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" Nucleic acids research 30
It contains a 2'-F modification on the sugar of deoxyadenosine (dA) with benzoyl (Bz) base protection
[3] Burmeister
THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol
1-N-Me-Pseudo UTP, 100mM Solution Application_mRNA " Nucleic acids research 30N1 methyl pseudouridine 5 triphosphate (m1TP) is a chemically modified uridine nucleotide designed for enzymatic incorporation into RNA during IVT using RNA polymerases such as T7 RNA polymerase. m1TP is an N1 methylated derivative of pseudouridine that preserves base pairing properties while altering innate immune recognition. When substituted for uridine in IVT, m1 reduces activation of innate immune sensors and enhances translational efficiency of
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