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Following TGF-beta binding
It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain
thereby acting as a critical on/off switch in innate antiviral immunity
as well as macrophage polarization
UniOne® TR-FRET Human cAMP Hirange Detection Kit OneStep ELISA Kit Following TGF-beta bindingProduct Specification Host Human Stability & Storage 80 Background The kit employs homogeneous time resolved fluorescence (TR FRET) technology, enabling precise measurement of cellular cAMP production. This method allows rapid detection of cAMP accumulation changes during the inhibition or activation of Gs or Gi signaling pathways. As shown in the figure, the Eu labeled anti cAMP antibody (TR FRET donor) and the Ac labeled cAMP (TR FRET acceptor) bind
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